butabarbital will lower the extent or impact of doxorubicin liposomal by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on.butabarbital will minimize the level or result of sufentanil by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Significance Not known.Butabarbital is also sold in combination with